Simulated galactic cosmic radiation exposure-induced mammary tumorigenesis in apcmin/+ mice coincides with activation of erα-errα-spp1 signaling axis

HIGHLIGHTS

• What: The study demonstrates that GCRsim exposure induces ductal overgrowth, increased duct density, and a heightened incidence of mammary tumors in ApcMin/+ mice. This study provides insights into the effects of GCRsim on mammary tissue biology, with implications for breast cancer risk after space radiation.
• Who: Kamendra Kumar and collaborators from the Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA have published the Article: Simulated Galactic Cosmic Radiation Exposure-Induced Mammary Tumorigenesis in ApcMin/+ Mice Coincides with Activation of ER-ERR-SPP1 Signaling Axis, in the Journal: Cancers 2024 . . .
  

   

  

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