: simultaneous curve fitting of functions and differential equations using analytical gradient calculations

HIGHLIGHTS

  • who: Julius B. Kirkegaard from the Niels Bohr Institute, University of Copenhagen, Copenhagen, Denmark have published the research work: : simultaneous curve fitting of functions and differential equations using analytical gradient calculations, in the Journal: (JOURNAL)
  • what: Simulatant provides a simple user interface to design complex fitting setups.

SUMMARY

    Expression, transcription networks, enzyme kinetics, and a host of other biological systems follow this trend. If experimental data is to be directly compared a theoretical model, the fits must be performed with numerical evaluation of the differential equations that define the theoretical models . . .

     

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