Simultaneous identification of functional antigen-specific cd8+ and cd4+ cells after in vitro expansion using elongated peptides

HIGHLIGHTS

  • who: Juliane Schuhmacher and collaborators from the Interfaculty Institute for Cell Biology, Department of Immunology, University of Tu00fcbingen, Tu00fcbingen, Germany have published the paper: Simultaneous Identification of Functional Antigen-Specific CD8+ and CD4+ Cells after In Vitro Expansion Using Elongated Peptides, in the Journal: Cells 2022, 3451 of /2022/
  • what: The authors show that not only CD8+ T_cell responses but also CD4+ T_cell responses can be suboptimally detected with EPs. Based on the results , the authors propose the use of 10 u00b5g/mL EP plus 20 u00b5g/mL Poly-ICLC on day 1, and 50 . . .

     

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