Simultaneous metabolite maldi-msi, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections

HIGHLIGHTS

  • who: Lisa Kreutzer from the Laboratory have published the research: Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections, in the Journal: (JOURNAL) of 10/02/2022
  • what: The authors aimed to test the feasibility of determining the spatially resolved metabolite level using MALDI-MSI, the genome level using WES, and the transcriptome level using RNA-seq from the same FFPE tissue sections. The authors show that method coupling of MALDI-MSI, WES, and RNA-seq is feasible and can generate technically sound and plausible data.
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