Single-cell analysis implicates th17-to-th2 cell plasticity in the pathogenesis of palmoplantar pustulosis

HIGHLIGHTS

• who: Daniel McCluskey MSc from the s Institute University of have published the research: Single-cell analysis implicates TH17-to-TH2 cell plasticity in the pathogenesis of palmoplantar pustulosis, in the Journal: (JOURNAL)
• what: The bulk and single-cell RNA sequencing data the authors report here have been uploaded to the publicly accessible Gene Expression Omnibus repository (www.ncbi.nlm.nih.gov/ geo; series accession no. GSE185858). Clinical trials of IL1 (anakinra) and IL-36 (spesolimab) blockers have been carried out on the assumption that PPP has an autoinflammatory pathogenesis, but the studies undertaken so . . .
  

   

  

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