Single-cell atlas reveals different immune environments between stable and vulnerable atherosclerotic plaques

HIGHLIGHTS

  • who: Peicong Ge and colleagues from the Sorbonne Universitu00e9s, France Southern of Science and have published the research: Single-cell atlas reveals different immune environments between stable and vulnerable atherosclerotic plaques, in the Journal: (JOURNAL)
  • how: The results showed that more CD86+CD68+ M1 pro-inflammatory macrophages were found in vulnerable plaques while CD4+T memory cells were mainly found in stable plaques. The authors used Mass Cytometry (Mass Cytometry CyTOF) a precise high-dimensional approach to identify the differences in immune microenvironment between stable and vulnerable plaques. This suggested the TNF-a mediated immune_responses . . .

     

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