Single-cell dna sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development

HIGHLIGHTS

  • who: Marina Danilenko from the Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK have published the article: Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development, in the Journal: (JOURNAL)
  • what: The authors report the application of sc-WGS to reconstruct the development and clonal evolution of 14 MBs, encompassing sampling of two spatially distinct regions of each tumour.
  • how: Individual tumour data were visualised using the "fishplot" R package (https//​www.​rstud​io.​com . . .

     

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