Single-cell gene expression analysis reveals β-cell dysfunction and deficit mechanisms in type 2 diabetes

HIGHLIGHTS

• who: Lichun Ma from the (UNIVERSITY) have published the research: Single-cell gene expression analysis reveals β-cell dysfunction and deficit mechanisms in type 2 diabetes, in the Journal: (JOURNAL)
• what: The analysis shows that T2D β-cells are normal in insulin gene expression in the scenario of low cellular stress (especially oxidative stress) but appear dysfunctional under the circumstances of high cellular stress. The authors aim to unravel the β-cell dysfunction and deficit mechanisms in T2D by analyzing the single-cell transcriptomic data of β-cells. The authors employed three datasets of β-cell transcriptomes, which were obtained . . .
  

   

  

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