HIGHLIGHTS
- who: Pengfei Chen from the University of Illinois, United States have published the research work: Single-Cell Landscape of Mouse Islet Allograft and Syngeneic Graft, in the Journal: (JOURNAL)
- how: These data indicated that islet-resident immune cells in baseline islet were very limited and only a small population of macrophages was identified (Supplementary Figures 2A-D). Together these results indicated that islet cells in the xenogeneic microenvironment were potentially transformed into antigen-presenting cell-like cells. These results indicated that this subcluster of mesenchymal cells may support the reorganization of grafted islet cells.
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