Single-cell rna profiling of plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets

HIGHLIGHTS

  • who: Anthony A. Ruberto from the National Institutes of Health (NIH), United States Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA have published the paper: Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets, in the Journal: (JOURNAL)
  • what: The authors show that by coupling the in_vitro liver stage model (Roth et_al, 2018; Maher et_al, 2021a) with a high-throughput single-cell capture technology (Klein et_al, 2015; Macosko et_al, 2015; Zheng et_al, 2017) that transcriptome-wide characterization of P. vivax-infected . . .

     

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