Single-cell rna sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high aqp4 expression

HIGHLIGHTS

• who: Ran Wang from the example, is upregulated in , macrophages but was also reported to be able to influence the balance between , and , macrophages and contribute to inducing , macrophage polarization [51, ], explaining the noticeable , type bias of macrophages in the high , groupA previous study has demonstrated that , blockade alleviated irradiated lung damage and inhibited activation of , macrophages [53]. However, similar studies related to brain tumors are absent at this moment. With trajectory analysis, we noticed that in the low , group, the expression of , is upregulated earlier than AQP4, indicating that , may play an upstream regulating role for . . .
  

   

  

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