HIGHLIGHTS
- who: Xiao Yu and collaborators from the China China have published the research: Single-cell sequencing and establishment of an 8-gene prognostic model for pancreatic cancer patients, in the Journal: (JOURNAL)
- how: The authors examined molecular and immune signatures and constructed a polygenic risk score model. The authors used LASSO regression to reduce the number of genes in the risk model by R package glmnet . The authors obtained immune cell markers associated with pancreatic cancer from previous studies including stellate cell (ADIRF) fibroblasts (COL1A1 COL1A2 and DCN) T_cells (CD2 CD3D CD3E and CD3G) B . . .
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