Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model

HIGHLIGHTS

• who: Tove Selvin from the DepartmentUppsala University have published the research work: Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model, in the Journal: Scientific Reports Scientific Reports of 25/02/2022
• what: A preliminary analysis indicated relatively few cells with a distinct transcriptional signature induced by FTD treatment at 12 h (see Supplementary Fig 2), hence the authors focused on HCT116 at the 72 h time-point where the difference was more pronounced. The authors explored the feasibility of utilizing scRNA-seq to simultaneously study transcriptional drug responses in cancer- and immune . . .
  

   

  

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