Single-cell transcriptome reveals cellular hierarchies and guides p-emt-targeted trial in skull base chordoma

HIGHLIGHTS

• who: Qilin Zhang from the Patients with SBC were recruited from the Department of Neurosurgery at Huashan Hospital affiliated to Shanghai Medical School, Fudan University from , to , for this studyThe diagnosis of SBC was made from clinical manifestations, laboratory tests, and imaging, and SBC was histologically confirmed in a blinded fashion by at least two senior pathologists after surgical resection. Subjects with previous malignant diseases or family history of SBC were excluded. The age and gender of human subjects providing patients are summarized in Supplementary Table, . Fresh biopsies of chordomas were collected at the time of surgical . . .
  

   

  

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