Single-cell transcriptomic ling reveals speci c maturation signatures in human cardiomyocytes derived from lmnb2 -inactivated induced pluripotent stem cells

HIGHLIGHTS

  • who: November et al. from the McGill Health Centre, Canada have published the research work: Single-cell transcriptomic ling reveals speci c maturation signatures in human cardiomyocytes derived from LMNB2 -inactivated induced pluripotent stem cells, in the Journal: (JOURNAL)
  • what: To investigate cellular heterogeneity during cardiomyocyte differentiation, the authors first characterized the single-cell transcriptome of human iPSC-CMs induced by modulating WNT signaling, and the authors report here the findings identifying cellular subpopulations and distinct developmental gene profiles that define cardiomyocyte maturity. The authors focused on the exit from the cell cycle as a . . .

     

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