Single-cell transcriptomic profiling unveils dysregulation of cardiac progenitor cells and cardiomyocytes in a mouse model of maternal hyperglycemia

HIGHLIGHTS

• who: Sathiyanarayanan Manivannan from the Center forState University have published the research: Single-cell transcriptomic profiling unveils dysregulation of cardiac progenitor cells and cardiomyocytes in a mouse model of maternal hyperglycemia, in the Journal: (JOURNAL) of 10/Dec/2021
• what: The authors report two key findings based upon scRNA-seq data generated in matHG-exposed embryonic hearts. The authors provide the experimental evidence of developmental toxicity of matHG on multiple cell lineages and focused the work on impaired CM function derived from the Isl1+SHF lineage. The authors demonstrated that the Isl1+ MP __NEWPAGE__ARTICLE and . . .
  

   

  

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