HIGHLIGHTS
- who: Seema C. Namboori from the Systems Institute University of Exeter, Exeter , QD, UK have published the paper: Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons, in the Journal: (JOURNAL) of December/14,/2021
- what: The authors focused on the V1 population for further analysis.
- how: The data indicated that iPSC-derived neuronal cultures display wide variation in expression across individual cells that is averaged in bulk analysis. The authors first decided to focus on MNs for further analysis. The authors implemented a k-nearest neighbors . . .
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