Single-chain fragment variable: recent progress in cancer diagnosis and therapy

HIGHLIGHTS

  • who: Paola Muu00f1oz-Lu00f3pez and collaborators from the ctor Mu00e1rquez, Mexico have published the article: Single-Chain Fragment Variable: Recent Progress in Cancer Diagnosis and Therapy, in the Journal: Cancers 2022, 14, 4206. of /2022/
  • what: The lack of stability of the VH-VL domains of scFvs is often the main reason underlying their lack of functionality and their tendency to aggregate .
  • how: This review describes the made with scFvs as a cancer diagnostic and therapeutic tool with an emphasis on preclinical approaches and their potential use in clinical trials.
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