Single-circulating tumor cell whole genome amplification to unravel cancer heterogeneity and actionable biomarkers

HIGHLIGHTS

  • who: Tanzila Khan et al. from the School of Medicine, Western Sydney University, Campbelltown, NSW, Australia have published the Article: Single-Circulating Tumor Cell Whole Genome Amplification to Unravel Cancer Heterogeneity and Actionable Biomarkers, in the Journal: (JOURNAL)
  • what: The authors provide an overview of recent advances in WGA and their applications in the genetic analysis of single CTCs along with prospective views towards clinical applications. The authors focus on the technical challenges of isolating and recovering single CTCs and then explore different WGA methodologies and recent developments which have been utilized to amplify single . . .

     

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