Single-keratinocyte transcriptomic analyses identify different clonal types and proliferative potential mediated by foxm1 in human epidermal stem cells

HIGHLIGHTS

  • who: Elena Enzo from the University of Center, Rozzano, Milan, Italy have published the research work: Single-keratinocyte transcriptomic analyses identify different clonal types and proliferative potential mediated by FOXM1 in human epidermal stem cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that genome-wide transcriptome analysis performed on single clonogenic primary human epidermal keratinocytes identifies categories of genes clearly distinguishing the different clonal types and discover the role of FOXM1 as a YAPdependent key regulator of normal and adhesion-defective epidermal stem_cells. The authors show that single-cell transcriptome analyses . . .

     

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