Single microcolony diffusion analysis in pseudomonas aeruginosa biofilms

HIGHLIGHTS

  • who: Jagadish Sankaran from the Published in partnership with Nanyang Technological University have published the article: Single microcolony diffusion analysis in Pseudomonas aeruginosa biofilms, in the Journal: (JOURNAL)
  • what: The authors used SPIM-FCS to investigate the influence of molecular size and charge on diffusion within microcolonies of P. aeruginosa of different size, age and stage to determine how the biofilm matrix influences molecular mobility and whether the structure of biofilms could be a reason for the reduced efficacy of antibiotics. Similar to observations in this study, using SPT, it was shown that positively charged . . .

     

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