Single molecule analysis of functionally asymmetric g protein-coupled receptor (gpcr) oligomers reveals diverse spatial and structural assemblies*⒦

HIGHLIGHTS

  • who: Kim C. Jonas from the (UNIVERSITY) have published the paper: Single Molecule Analysis of Functionally Asymmetric G Protein-coupled Receptor (GPCR) Oligomers Reveals Diverse Spatial and Structural Assemblies*⒦, in the Journal: (JOURNAL) of February/13,/2015
  • what: This approach has been previously validated for assessing associating molecules in single and two channel PALM data sets . The authors focused on lower order oligomers for this analysis as the formation of trimers and tetramers displayed a weak or no correlation with receptor density (r ⫽ 0.40 for trimers; r ⫽ 0.26 for tetramers). The authors propose . . .

     

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