HIGHLIGHTS
- who: Andrea M. Reyes-Ortiz from the of Biological Chemistry, University of California, Irvine, Irvine, CA, USA have published the research work: Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits, in the Journal: (JOURNAL) of January/20,/2023
- what: Findings from this model system can be compared to in_vivo mouse and other HD model systems to evaluate common and novel HD phenotypes. The aims of this study are to further characterize astrocyte cell states in unaffected and HD contexts, identify drivers of transcriptional dysregulation, and to compare . . .
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