Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors

HIGHLIGHTS

• who: O. C. Bedoya-Reina from the Karolinska Institute University of have published the paper: Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• how: The authors identified a population of cells unique to postnatal human adrenal gland that presented precursor features of chromaffin cells namely the expression of progenitor and migratory markers (i.e. NTRK2 ERBB3 BCL11A ASXL3 RTTN SOX6 DOCK7 LAMA3 SEMA3E and CLDN11) a high differentiation potential and_(3) a computed (by RNA velocity) directionality of . . .
  

   

  

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