HIGHLIGHTS
- who: Cecilia Wieder from the Division of Systems Medicine, College London, London, UK have published the research: Single sample pathway analysis in metabolomics: performance evaluation and application, in the Journal: (JOURNAL)
- what: The authors provide a benchmark of established ssPA methods (ssGSEA GSVA SVD (PLAGE) and z-score) alongside the evaluation of two novel methods the authors propose: ssClustPA and kPCA using semi-synthetic metabolomics data. A typical metabolomics analysis workflow usually involves identifying a subset of metabolites of interest in relation to the study objective, which can be achieved in various ways not limited . . .
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