Sirna-mediated timp1 silencing inhibited the inflammatory phenotype during acute lung injury

HIGHLIGHTS

  • who: Ivan V. Chernikov and colleagues from the Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences have published the Article: siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury, in the Journal: (JOURNAL) of 10/08/2019
  • what: The authors show that siRNA-mediated prevention of Timp1 activation during LPS-induced ALI significantly decreased pro-inflammatory changes in the lung tissue. All these factors point to the prospects for Timp1 silencing as an approach to therapy of not only acute inflammatory changes in the lung . . .

     

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