HIGHLIGHTS
- who: Yan Zhang and Anshi Wu and Changwei Wei from the Huazhong University of Science and Technology, China have published the research: SIRT1 activation attenuates microglia-mediated synaptic engulfment in postoperative cognitive dysfunction, in the Journal: (JOURNAL)
- what: The authors demonstrate that anesthesia and surgery induce SIRT1 dysfunction and microglial activation in the hippocampus of a POCD mouse model.
- future: Investigation is needed to address these issues.
SUMMARY
While neuroinflammation, increased oxidative stress, deposition of amyloid-beta, and hyperphosphorylation of tau protein have all been implicated in its development . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.