Sirt1 regulates microglial activation and inflammation following oxygen-glucose deprivation/reoxygenation injury by targeting the shh/gli-1 signaling pathway

HIGHLIGHTS

  • who: Hongyan Liao from the Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Youyi Road, Yuzhong District, Chongqing, China have published the research: Sirt1 regulates microglial activation and inflammation following oxygen-glucose deprivation/reoxygenation injury by targeting the Shh/Gli-1 signaling pathway, in the Journal: (JOURNAL)
  • what: The aim of this study is to mainly investigate the effect of Sirt1 on oxygen-glucose deprivation/reoxygenation (OGD/R)-treated N9 microglia following treatment with the Sirt1 agonists resveratrol and SRT1720 and the Sirt1 antagonist sirtinol. This study demonstrated that stimulation with the . . .

     

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