HIGHLIGHTS
- who: Anugraha Gandhirajan and collaborators from the Federal University of Pernambuco, Brazil have published the research work: SIRT2-PFKP interaction dysregulates phagocytosis in macrophages with acute ethanol-exposure, in the Journal: (JOURNAL)
- what: In the current project, the authors aimed to elucidate the mechanism by which ethanol-induced SIRT2 regulates the innate immune function of bacterial clearance, phagocytosis, LAP, and cellular metabolism, using mouse-bone marrow- and human blood monocytederived macrophages. The authors show that the SIRT2 deficiency (genetic deficiency or pharmacological inhibition) stabilizes PFKP expression, preserves acetylation of PFKP and glycolysis in response to . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.