HIGHLIGHTS
- who: SIRT and collaborators from the (UNIVERSITY) have published the research: SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis, in the Journal: (JOURNAL)
- what: In the adaptation of this model, it is proposed that in a fed state, the cells sense that energy packets (i.e., food) are readily abundant and as such, cellular processes are activated.
- future: The logical extension of this idea is that the loss of SIRT3 activity by one of several potential mechanisms would create a cellular environment permissive for age-related cancers . . .
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