HIGHLIGHTS
- who: Shanjiang Zhao from the Sciences, Beijing, China have published the paper: Sirtuin 3 regulation: a target to alleviate u03b2-Hydroxybutyric acid-induced mitochondrial dysfunction in bovine granulosa cells, in the Journal: (JOURNAL)
- what: The aim of this study was to explore the protection effects and underlying mechanisms of Sirt3 against BHBA overload-induced damage of fGCs. This study provides new strategies to mitigate the fGCs injury caused by excessive BHBA stress in dairy cows with ketosis. These results suggested that high concentrations of BHBA (2.4 mmol/L) may trigger apoptosis in bovine fGCs . . .
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