Sirtuin 7 inhibitor attenuates colonic mucosal immune activation in mice—potential therapeutic target in inflammatory bowel disease

HIGHLIGHTS

  • who: Sanghyun Kim and collaborators from the Department of Internal Medicine, College of Medicine, University, have published the research work: Sirtuin 7 Inhibitor Attenuates Colonic Mucosal Immune Activation in Miceu2014Potential Therapeutic Target in Inflammatory Bowel Disease, in the Journal: Biomedicines 2022, 2693 of /2022/
  • what: The authors also observed that the degree of clinical inflammation was improved in SIRT7-treated the study demonstrated that SIRT7 inhibition attenuated the inflammatory response in the colon of suggesting a possible role for SIRT7 in the pathogenesis of immune-mediated intestinal inflammation. The authors successfully evaluated a novel pathway . . .

     

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