HIGHLIGHTS
- who: COPYRIGHT and collaborators from the Medical University of Warsaw, Poland have published the research: Sirtuins functions in central nervous system cells under neurological disorders, in the Journal: (JOURNAL)
- how: The result is consistent with a previous study that SIRT1 deficiency in microglia contribute to aging and neurodegeneration-related cognition decline importantly in this article they proved that SIRT1 exert neuroprotection through hypomethylating the specific CpG sites on IL-1u03b2 proximal promoter which is a classic inflammatory factor (Cho et_al 2015).
- future: Study is required to determine roles of SIRT3 in the two . . .
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