HIGHLIGHTS
- who: Yikai Liu from the Yamaguchi University, Japan have published the research work: Sirtuins in osteoarthritis: current understanding, in the Journal: (JOURNAL)
- future: These characteristics suggest that activating the AMPK pathway or promoting SIRT activity may contribute to cellular energy store maintenance and anabolic activity restoration.
SUMMARY
Osteoarthritis (OA) is a prevalent disease characterized by severe joint pain and loss of joint function, which creates a large burden for elderly patients and seriously reduces their quality of life. Reduced SIRT1 and SIRT6 levels have been found in osteoarthritic cartilage, and conditional . . .
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