Skeletal muscle cells derived from induced pluripotent stem cells: a platform for limb girdle muscular dystrophies

HIGHLIGHTS

  • who: Celine Bruge and collaborators from the , Stem, Corbeil-Essonnes, France have published the research: Skeletal Muscle Cells Derived from Induced Pluripotent Stem Cells: A Platform for Limb Girdle Muscular Dystrophies, in the Journal: Biomedicines 2022, 1428 of 28/04/2022
  • what: The authors report that skMC derived from hiPSC express the majority of the genes and proteins that cause LGMD. As a proof of concept the authors demonstrate the importance of this cellular model for studying LGMDR9 by evaluating disease-specific phenotypes in skMC derived from hiPSC obtained from four patients. The authors report . . .

     

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