Skp2 attenuates autophagy through beclin1-ubiquitination and its inhibition reduces mers-coronavirus infection

HIGHLIGHTS

• who: Nils C. Gassen from the Max Planck Institute University of Bonn, Venusberg Campus, Bonn, Germany have published the Article: SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors aim to elucidate the mechanisms controlling BECN1 protein levels. Since the authors aimed at understanding the mechanism of FKBP51directed increase in BECN1, the authors focussed in the following on proteins the authors found associated with both FKBP51 and BECN1. This work reveals BECN1 as a target of the E3 ligase SKP237,38 . . .
  

   

  

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