Skp2 regulates subcellular localization of pparγ by mek signaling pathways in human breast cancer

HIGHLIGHTS

  • who: Hongge Cheng and colleagues from the Department of Laboratory Science, the Fourth Hospital Affiliated to Guangxi Medical University, Jiangsu, China have published the research work: Skp2 Regulates Subcellular Localization of PPARγ by MEK Signaling Pathways in Human Breast Cancer, in the Journal: (JOURNAL)
  • what: In this study the role of cytoplasmic PPARγ and Skp2 expression was investigated in human breast cancer progression.
  • how: Showed that the expression __NEWPAGE__Int. correlated significantly with estrogen receptor (p = and pathological grade (p = respectively. The results showed that PPARγ was exported from the cytosol toward the nucleus . . .

     

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