Slc-0111, an inhibitor of carbonic anhydrase ix, attenuates hepatoblastoma cell viability and migration

HIGHLIGHTS

  • who: Katja Eloranta from the Department of General Surgery, Qilu Hospital of Shandong University, China have published the research work: SLC-0111, an inhibitor of carbonic anhydrase IX, attenuates hepatoblastoma cell viability and migration, in the Journal: (JOURNAL) of December/31,/2017
  • what: The authors characterize CAIX expression in archival HB specimens and use cell culture models to study the impact of SLC0111 on this malignancy. The authors show that hypoxia induces CAIX expression in HB cells and that SLC-0111 has considerable in_vitro activity against this cancer. This approach has improved the 5-year . . .

     

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