HIGHLIGHTS
- who: Qi Cao from the (UNIVERSITY) have published the article: SLC17A9 Protein Functions as a Lysosomal ATP Transporter and Regulates Cell Viability*, in the Journal: (JOURNAL) of August/15,/2014
- what: The authors report that SLC17A9 is highly enriched in lysosomes and actively transports ATP into lysosomes. Using quinacrine staining, a bioluminescent ATP assay, and ATP uptake assays, the authors provide strong evidence that SLC17A9 is responsible for lysosomal ATP accumulation. The authors propose that defects in ATP uptake and accumulation induced by DIDS were primarily due to SLC17A9 inhibition. The authors conclude this for . . .
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