Sleeping beauty generated cd19 car t-cell therapy for advanced b-cell hematological malignancies

HIGHLIGHTS

  • who: Harjeet Singh et al. from the United Kingdom University of Southampton have published the paper: Sleeping beauty generated CD19 CAR T-Cell therapy for advanced B-Cell hematological malignancies, in the Journal: (JOURNAL)
  • what: The aims were to determine the safety profile and maximum tolerated dose (MTD) of SB CAR T-cells. The authors report on the long-term findings of non-viral, SB generated, autologous CD19 directed CAR T-cells in patients with advanced lymphoid malignancies. The intent of this trial was to investigate whether modifications to the CAR T product would increase . . .

     

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