Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics

HIGHLIGHTS

  • who: Jung-A. A. Woo and David E. Kang from the University of Texas Health Science Center at Houston, United States have published the Article: Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics, in the Journal: (JOURNAL)
  • what: The studies showed that Au03b2 oligomers and misfolded tau not only increase sEV secretion but are also secreted in association with sEVs.
  • how: For treatment with Au03b242o the authors used mouse hippocampusderived HT22 neuroblastoma cells as HT22 cells are responsive to Au03b242o . . .

     

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