HIGHLIGHTS
- who: Lukas Kaltenbach from the (UNIVERSITY) have published the article: Slow integrin-dependent migration organizes networks of tissue-resident mast cells, in the Journal: (JOURNAL) of 15/03/2023
- what: The authors show that the movement of mast cells (immune cells with important roles during allergy and anaphylaxis) differs fundamentally from the widely applied paradigm of interstitial immune cell migration. Together, the authors demonstrate that MC migration in physiological 3D environments strictly depends on integrin-mediated force coupling, which is required to organize the resident MC population and distribute individual MCs widely throughout interstitial spaces . . .
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