Slow muscles guide fast myocyte fusion to ensure robust myotome formation despite the high spatiotemporal stochasticity of fusion events

HIGHLIGHTS

  • who: Mario A. Mendieta-Serrano from the Institut National University Warwick, Coventry , AL, UK have published the paper: Slow muscles guide fast myocyte fusion to ensure robust myotome formation despite the high spatiotemporal stochasticity of fusion events, in the Journal: (JOURNAL) of September/12,/2022
  • what: The authors show that the expression of the fusogen myomaker is permissive but not instructive determining the spatiotemporal fusion pattern. The authors propose a model which slow muscles guide fast myocytes by funneling them close together enhancing fusion probability. This model has not been tested at a tissue scale . . .

     

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