HIGHLIGHTS
- who: Nabil Parkar from the University of Ottawa, Canada have published the research work: Slowed gastrointestinal transit is associated with an altered caecal microbiota in an aged rat model, in the Journal: (JOURNAL)
- what: The aim of this study was to examine how slowed GI transit due to opioid receptor agonism in the ENS affects the caecal microbiota. Through the experiments the authors have previously shown that loperamide works by inhibiting enteric neuronal activity, delays GI transit, inducing constipation in aged rats (Dalziel et_al, 2016). The authors investigated if changes in microbiota is associated with . . .
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