Smad2/3 mediate oncogenic effects of tgf-β in the absence of smad4

HIGHLIGHTS

• who: Adrien Bertrand-Chapel from the Centre Convergence Plascan, Lyon, FranceRousse University have published the Article: SMAD2/3 mediate oncogenic effects of TGF-u03b2 in the absence of SMAD4, in the Journal: (JOURNAL) of 14/09/2022
• what: The authors provide evidence that the oncogenic properties of in SMAD4-negative BxPC-3 cells are associated with the activation of a transcriptional program triggered by SMAD2 and SMAD3.
• how: Similar results were obtained using S2-KD S3-KD S2/3-KD BxPC-3 (Fig S2b c) and S2/3-KD Capan-1 cells (Fig . . .
  

   

  

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