Smad6 determines bmp-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model

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  • who: Miriam de Boeck from the DepartmentLeiden University University, Tokyo, Japan have published the article: Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model, in the Journal: Scientific Reports Scientific Reports
  • what: The authors have made use of two ER- cell lines and shown the importance of BMP signalling in EMT and for in_vivo invasion. This model has previously been used to show the importance of TGF-β signalling in MDA-MB-231 invasion28. This study shows an additional benefit of the zebrafish xenograft model by clearly showing changes in . . .

     

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