Small fiber involvement is independent from clinical pain in late-onset pompe disease

HIGHLIGHTS

• who: Elena K. Enax-Krumova from the Corneal confocal microscopy (CCM) was available in only one of the study centers and as a proof of concept four patients underwent additionally a detailed assessment of the corneal innervation by CCMFour CCM images from the left eye of each patient were manually analyzed using an established software (CCMetrics, Version, .0, M.A. Dabbah, University of Manchester) to visualize the corneal subbasal nerve plexus. The average corneal nerve fiber length (CNFL, mm/mm2), density (CNFD, nerves/mm2), and branch density (CNBD, branch points) were analyzed and compared to normative data . . .
  

   

  

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