Small molecule egfr inhibitors as anti-cancer agents: discovery, mechanisms of action, and opportunities

HIGHLIGHTS

  • who: Tanzida Zubair and Debasish Bandyopadhyay from the Department of Chemistry, The University of Texas Rio Grande Valley, West University Drive, Edinburg, TX, USA have published the research: Small Molecule EGFR Inhibitors as Anti-Cancer Agents: Discovery, Mechanisms of Action, and Opportunities, in the Journal: (JOURNAL)

SUMMARY

    Epidermal growth factor receptor (EGFR) inhibitors are a class of drugs that are used to treat several common malignancies, including breast, colon, lung, and pancreatic cancer. Epidermal growth factor receptor (EGFR) has four different members, with similar structural features, such as EGFR (HER1/ErbB1), ErbB2 (HER2 . . .

     

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