HIGHLIGHTS
- who: Top from the Universidad de La Frontera, Temuco, McKusick-Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA have published the research: Small molecule inhibitor screening identifified HSP90 inhibitor, in the Journal: (JOURNAL)
- how: The authors evaluated antitumoral activity of HSP90 inhibitors 17-AAG and geldanamycin in_vitro and on a preclinical subcutaneous tumor model and showed the potential of the 17-AAG for further clinical investigations. Cells were evaluated on a FACSCanto II (Becton Dickinson Franklin Lake NJ) and data was analyzed with BD FACSDiva software version
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