Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor pex5 is toxic to trypanosoma

HIGHLIGHTS

• who: Valeria Napolitano from the Jagiellonian University have published the Article: Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma, in the Journal: Scientific Reports Scientific Reports
• how: Data were analyzed using Origin Pro 9.0.

SUMMARY

Adverse effects of a required long-term treatment frequently lead to discontinuation and treatment failure. Docking of the PEX5-cargo complex at PEX14 results in formation of a dynamic transient import pore which allows translocation of cargo into the glycosomal l­umen14. Dawidowski et_al demonstrated that . . .

 



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